Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA2 All Species: 14.55
Human Site: T2351 Identified Species: 26.67
UniProt: Q9BZC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BZC7 NP_001597 2435 269873 T2351 E D Y S V S Q T T L D N V F V
Chimpanzee Pan troglodytes XP_001152577 2346 264166 F2261 D L N P V E Q F F Q G N F P G
Rhesus Macaque Macaca mulatta XP_001117819 2476 273629 T2378 E D Y S V S Q T T L D N V F V
Dog Lupus familis XP_537788 2395 264756 T2303 E D Y S V S Q T T L D N V F V
Cat Felis silvestris
Mouse Mus musculus P41234 2434 270490 S2350 G I E D Y S V S Q T T L D N V
Rat Rattus norvegicus Q9ESR9 2434 270910 S2350 G I E D Y S V S Q T T L D N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 Y2183 K H R N M L Q Y Q L P S S L S
Chicken Gallus gallus XP_422330 2276 256293 E2193 F P G S L Q R E K H Y N M L Q
Frog Xenopus laevis NP_001089022 2363 267334 Q2277 T N F P G S V Q R E K H Y N M
Zebra Danio Brachydanio rerio NP_001139161 2268 254351 Y2185 K H R N M L Q Y Q L S S S L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 L1621 V Q L V Q T R L P N S V L K T
Sea Urchin Strong. purpuratus XP_798273 1913 213253 F1830 C I G Y C P Q F D A L F D E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 F1798 G G I P L P I F A E W W L T K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 96 82.2 N.A. 91 92.9 N.A. 39.1 35.7 36.5 37.7 N.A. N.A. N.A. 23.7 41.7
Protein Similarity: 100 52 96.6 86.1 N.A. 93.2 94.9 N.A. 55.7 53.5 54.7 54.5 N.A. N.A. N.A. 39 54.4
P-Site Identity: 100 20 100 100 N.A. 13.3 13.3 N.A. 13.3 13.3 6.6 13.3 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 20 20 N.A. 40 33.3 33.3 40 N.A. N.A. N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 26.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % A
% Cys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 24 0 16 0 0 0 0 8 0 24 0 24 0 0 % D
% Glu: 24 0 16 0 0 8 0 8 0 16 0 0 0 8 0 % E
% Phe: 8 0 8 0 0 0 0 24 8 0 0 8 8 24 0 % F
% Gly: 24 8 16 0 8 0 0 0 0 0 8 0 0 0 8 % G
% His: 0 16 0 0 0 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 24 8 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 16 0 0 0 0 0 0 0 8 0 8 0 0 8 8 % K
% Leu: 0 8 8 0 16 16 0 8 0 39 8 16 16 24 8 % L
% Met: 0 0 0 0 16 0 0 0 0 0 0 0 8 0 8 % M
% Asn: 0 8 8 16 0 0 0 0 0 8 0 39 0 24 0 % N
% Pro: 0 8 0 24 0 16 0 0 8 0 8 0 0 8 0 % P
% Gln: 0 8 0 0 8 8 54 8 31 8 0 0 0 0 8 % Q
% Arg: 0 0 16 0 0 0 16 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 0 31 0 47 0 16 0 0 16 16 16 0 8 % S
% Thr: 8 0 0 0 0 8 0 24 24 16 16 0 0 8 16 % T
% Val: 8 0 0 8 31 0 24 0 0 0 0 8 24 0 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % W
% Tyr: 0 0 24 8 16 0 0 16 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _